Close  

Researchers identify erectile dysfunction gene

/ 07:35 AM October 09, 2018

WASHINGTON, United States – Researchers have identified a genetic variant that raises the probability of erectile dysfunction, a development that could help improve treatment, according to a study published Monday in a US journal.

ADVERTISEMENT

Men who have a copy of this variant have a 26 percent increased risk of facing erectile dysfunction compared to the average population, said the findings in the Proceedings of the National Academy of Sciences.

Those with two copies of the variant face a 59 percent higher risk, according to geneticist Eric Jorgenson, the study’s lead author.

FEATURED STORIES

The results were based on a database of 36,649 patients of Kaiser Permanente Northern California.

The average population risk is of one in five men, according to a 2007 study in the United States, but the ratio increases sharply with age.

About a third of erectile dysfunction risk is linked to genetic factors. According to the new study, the genetic variant Jorgenson and his colleagues identified alone accounts for two percent of the risk.

Obesity, diabetes and cardiovascular disease all have genetic components and are also linked to erectile dysfunction.

“We know that there are other factors for ED including smoking, obesity, diabetes and cardiovascular disease, and men who address those factors can reduce their risk of ED,” Jorgenson told AFP.

“Because the region that we identified in the human genome appears to act independently of those risk factors, developing new treatments that target the variation in this genetic location has the potential to help those men who do not respond to current treatment.”

He noted that about 50 percent of men do not respond to erectile dysfunction treatments currently available.

ADVERTISEMENT

The study’s results were validated by studying a second database in Britain. /cbb

Read Next
LATEST STORIES
MOST READ
Don't miss out on the latest news and information.
View comments

Subscribe to INQUIRER PLUS to get access to The Philippine Daily Inquirer & other 70+ titles, share up to 5 gadgets, listen to the news, download as early as 4am & share articles on social media. Call 896 6000.

TAGS: erectile dysfunction, genes, Health, Research
For feedback, complaints, or inquiries, contact us.



© Copyright 1997-2019 INQUIRER.net | All Rights Reserved

We use cookies to ensure you get the best experience on our website. By continuing, you are agreeing to our use of cookies. To find out more, please click this link.